Professor Richard Grundy, Director of Children’s Brain Tumour Research Centre (CBTRC)
It is clear that improvement in our ability to cure children with brain tumours and reduce the considerable morbidity will only come through a better understanding of the underlying biology of these varied and presently difficult to treat tumours. The principal aim of my research is based on this philosophy. Our research programme includes the use of DNA and RNA microarray technologies to identify biological correlates of tumour behaviour; to elucidate the underlying molecular alterations of each tumour type and to validate novel targets for the development of new drug therapies. In addition to my research activities at the Children’s Brain Tumour Research centre, I also have an active interest in the development and conduct of clinical trials in CNS tumours and am a long standing member of the Children’s Cancer Leukaemia Group CNS division. I am Chief investigator of the International Society of Paediatric Oncology Ependymoma study and heavily involved in discussions over the next Ependymoma trial. I am also Chair of the Biology Committee of the UK Paediatric Brain Tumour Consortium and am a Co-Investigator on a number of Children’s Cancer Leukaemia, Group Clinical and Biological studies.
We have a major research programme investing the molecular gemetoc of childhood brain tumours using cutting edge high resolution genetic analysis. We are developing biostatistical infrastructure to maximise the use of the data in our increasingly large data base.
Established in 1997, the Children’s Brain Tumour Research Centre brings together a multi-disciplinary team of leading healthcare professionals and researchers ─ all experts in their fields, and all committed to improving our understanding of childhood brain tumours.
Our team of experts draw on a huge range of experience in:
Their findings guide national and international developments in brain tumour research and clinical practice, leading to new methods of research to help find a cure, whilst minimising the risk of disability.
Donations and our research
We use every penny donated to triple our research funding, by attracting further external grants. And because people are at the heart of everything we do, our money is invested in:
the latest, cutting-edge equipment
making sure we have the best possible people in place
It’s our people who enable us to propel our research capability forward, while continuing to deliver groundbreaking results for patients and their families.
From the moment a patient realises something is wrong, through diagnosis, treatment and recovery, our research is there guiding and informing the work of healthcare professionals to bring new hope to brave young children.